Is CBD really the panacea?

The relationship in between infection and conventional antibiotics

Could CBD be useful in the battle against resistant bacterial strains? The arise from the University of Queensland in Australia recommend that it is possible. However prior to taking a look at the study in depth, it works to understand the development of the relationship in between bacteria and antibiotics.

Considering that the revolutionary discovery of penicillin by Alexander Fleming in 1928, antibiotics have actually been an important tool in the battle against bacteria and infections. And although we still utilize the very same proven methods today, bacteria have actually progressed. When exposed to antibiotics, specific bacteria, fungis and parasites are able to adapt and cancel the efficiency of the drug by establishing resistance.

It’s worth pointing out that antimicrobial resistance was most likely to happen anyway, as the genetic code for bacteria modifications gradually. However, it is believed that the overuse of antibiotics is an important factor that speeds up the development of resistant strains.

According to the World Health Organization, antimicrobial resistance “is a significantly major threat to global public health that needs action in all sectors of government and in society.” This has actually led researchers to think outside package by trying to recognize compounds that could be helpful in the battle against hazardous bacteria. Among these compounds is cannabidiol (CBD), a cannabinoid discovered in Cannabis sativa.

Researchers are searching for new methods to assault infections and resistant bacteria.

Dr. Mark Blaskovich, Principal Investigator and Program Coordinator for the Community for Open Antimicrobial Drug Discovery and Senior Research Officer at the Institute for Molecular Bioscience at the University of Queensland, concluded that CBD is effective against Gram-positive bacteria. Strains of Gram-positive bacteria consist of Staphylococcus aureus (common in skin infections) and Streptococcus pneumoniae (common in bacterial pneumonia).

Dr. Blaskovich provided his findings at an annual conference of the American Society for Microbiology. In vitro samples of both types of gram-positive bacteria were treated with artificial CBD. The results led Dr. Blaskovich to the conclusion that CBD operates at levels similar to those of prescription antibiotics vancomycin and daptomycin. He also found that CBD appeared to work against gram-positive strains of resistant bacteria, which many traditional antibiotics are starting to stop working.

” In particular, the activity was picked against the resistant strains of Staphylococcus aureus (MRSA, VISA, SARV), Streptococcus pneumoniae (MDR), and Enterococcus faecalis (ERV). Cannabidiol was bactericidal, had a low tendency to induce resistance and was active against MRSA biofilms. “

The team also performed another study using topical CBD to deal with a skin infection in mice. Once again, although the results were positive, CBD did not appear to eliminate the infection, but merely to decrease the number of bacterial cells.

Could CBD become an antibiotic?

While it is simple to hail this work as a substantial advancement in the anti-bacterial capabilities of CBD, it is prematurely to give up on penicillin.

Although it is believed that the efficiency of component CBD might come from the method it assaults the biofilm surrounding bacterial cells, the authors are still unsure of the mechanism of action of CBD. They also did not hesitate to point out the shortcomings of the study. Dr. Blaskovich mentioned that since the results are in the preliminary stages, it is far prematurely for people to begin treating their CBD infections themselves.

The study was also performed in vitro (outside the body), and there is a danger that the results of scientific trials will not be the same. Several compounds have actually revealed anti-bacterial efficacy in petri meals, but then failed at this important phase. It needs to also be discussed that the two research studies were carried out in collaboration with Botanix Pharmaceuticals Ltd, a pharmaceutical business concentrating on topical CBD Flavor products.

However, this research study could be an important step forward for CBD and the battle against antimicrobial resistance. CBD continues to have a great security profile and is not considered harmful even in large quantities. Luckily, Dr. Blaskovich and his team plan to continue their research study.

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